Dr. William C. Mobley

Scientific Advisory Board


Dr. William C. Mobley is John E. Cahill Family Professor in the Stanford University School of Medicine, Professor of Pediatrics, Professor by courtesy, of Neurosurgery, and director of the Neuroscience Institute at Stanford University. He completed both his M.D. and Ph.D. in Neuro- & Behavioral Science at Stanford. Mobley completed a residency and fellowship in neurology at Johns Hopkins University Hospital. In 1985, he joined the faculty of the University of California, San Francisco School of Medicine, rising to the rank of professor of neurology, pediatrics and neuroscience and serving as director of child neurology. In 1991, he was named the Derek Denny Brown Scholar of the American Neurological Association. From 1997 to 2005, he served as chair of the Department of Neurology and Neurological Sciences at Stanford, where he held the John E. Cahill Family Endowed Chair. He was appointed director of the Neuroscience Institute at Stanford and director of the Center for Research and Treatment of Down syndrome. Dr. Mobley is a Fellow Royal College of Physicians; a Member, Institute of Medicine, National Academy of Sciences; and received the 2004 Cotzias Award, American Academy of Neurology.

Dr. Mobley's research interests focus on understanding Down syndrome and Alzheimer's disease through identification of potential mechanisms for linking failed neurotrophin signaling to neurodegeneration. "Advances in understanding neurotrophic factors and their signaling pathways have provided insights into normal growth, survival and differentiation of neurons. Stimulated by neuropathological and genetic discoveries, studies in cell and animal models of neurodegenerative disorders have begun to clarify pathogenetic mechanisms of disease. My lab examines the intersection of these research themes, and identifies potential mechanisms for linking failed neurotrophin signaling to neurodegeneration."